Investment Q&A

• Home Depot Inc. (The) (HD $383.79)
  • $383.79 P/E (TTM): 26.3X Cap: $382.01B
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• Nike Inc. (NKE $69.09)
  • $69.09 P/E (TTM): 35.34X Cap: $102.12B
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• United Airlines Holdings Inc. (UAL $98.09)
  • $98.09 P/E (TTM): 9.67X Cap: $31.75B
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• Suncor Energy Inc. (SU $57.00)
  • $57.00 P/E (TTM): 12.44X Cap: $69.15B
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• Canadian Natural Resources Limited (CNQ $45.55)
  • $45.55 P/E (TTM): 11.49X Cap: $95.14B
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• Cenovus Energy Inc. (CVE $24.71)
  • $24.71 P/E (TTM): 17.13X Cap: $45.03B
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• Air Canada Voting and Variable Voting Shares (AC $18.46)
  • $18.46 P/E (TTM): 4.98X Cap: $5.46B
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• Teck Resources Limited Class B Subordinate Voting Shares (TECK.B $60.01)
  • $60.01 P/E (TTM): 105.04X Cap: $29.36B
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• Secure Waste Infrastructure Corp. (SES $19.76)
  • $19.76 P/E (TTM): 23.35X Cap: $4.56B
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• Capstone Copper Corp. (CS $13.74)
  • $13.74 P/E (TTM): 90.5X Cap: $10.47B
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• SPDR Biotech ETF (XBI $105.44)
  • $105.44 P/E (TTM): 15.46X Cap: $6.26B
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• Crocs Inc. (CROX $81.10)
  • $81.10 P/E (TTM): 21.62X Cap: $4.30B
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• Deckers Outdoor Corporation (DECK $101.58)
  • $101.58 P/E (TTM): 15.67X Cap: $14.53B
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• Stellantis N.V. (STLA $10.80)
  • $10.80 Cap: $31.25B
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Q: Sell or not, and proxy for sales in your opinion.
AC, TECK.B, CS, SES, STLA, ARE, CVE.
XBI-N, HD-N, NIKE-N,

Upvote 4

Read Answer Asked by Nizar on April 30, 2025

• iShares Global Healthcare Index ETF (CAD-Hedged) (XHC $67.58)
  • $67.58 P/E (TTM): 25.66X Cap: $502M
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• iShares U.S. Medical Devices ETF (IHI $60.47)
  • $60.47 P/E (TTM): 28.17X Cap: $4.15B
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• SPDR Biotech ETF (XBI $105.44)
  • $105.44 P/E (TTM): 15.46X Cap: $6.26B
  • View XBI Profile
  • View Questions on XBI

Q: Greetings…I’ve taken a 10% haircut on this ETF held for healthcare exposure. I could book the loss, but if I replace with another healthcare ETF inside of 30 days in your experience does the CRA have a problem with that? Also, some of the other ETF’s on the TSX look like they have fared even worse. Any ideas? (Trying to avoid holding one or two US companies individually)

Upvote 1

Read Answer Asked by Stephen R. on April 23, 2025

• iShares Biotechnology ETF (IBB $151.99)
  • $151.99 P/E (TTM): 18.7X Cap: $6.18B
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• SPDR Biotech ETF (XBI $105.44)
  • $105.44 P/E (TTM): 15.46X Cap: $6.26B
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• Natera Inc. (NTRA $172.09)
  • $172.09 Cap: $23.61B
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• ARK Genomic Revolution ETF (ARKG $32.13)
  • $32.13 P/E (TTM): 22.05X Cap: $1.02B
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• Catalyst Pharmaceuticals Inc. (CPRX $20.39)
  • $20.39 P/E (TTM): 12.56X Cap: $2.54B
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Q: It looks like biotech stocks are on a tear, especially those that may benefit from AI. Do you have any names that you might recommend? I'm considering the Arkg fund but I don't quite trust Cathy Woods after losing money on the Arkk fund in 2021. Thank you,

Jason

Upvote 6

Read Answer Asked by Jason on February 18, 2025

• Biogen Inc. (BIIB $150.97)
  • $150.97 P/E (TTM): 14.57X Cap: $22.13B
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• Gilead Sciences Inc. (GILD $118.25)
  • $118.25 P/E (TTM): 23.22X Cap: $146.72B
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• Illumina Inc. (ILMN $97.78)
  • $97.78 P/E (TTM): 12.98X Cap: $15.02B
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• AbbVie Inc. (ABBV $231.24)
  • $231.24 P/E (TTM): 110.14X Cap: $408.49B
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• Abbott Laboratories (ABT $134.27)
  • $134.27 P/E (TTM): 16.78X Cap: $233.69B
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• Eli Lilly and Company (LLY $845.72)
  • $845.72 P/E (TTM): 55.14X Cap: $800.43B
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• Novo Nordisk A/S (NVO $59.61)
  • $59.61 P/E (TTM): 16.77X Cap: $363.68B
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• iShares Biotechnology ETF (IBB $151.99)
  • $151.99 P/E (TTM): 18.7X Cap: $6.18B
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• SPDR Biotech ETF (XBI $105.44)
  • $105.44 P/E (TTM): 15.46X Cap: $6.26B
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• First Trust NYSE Arca Biotechnology ETF (FBT $33.17)
  • $33.17 P/E (TTM): 22.78X Cap: $1M
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Q: Hi 5i, can you give me the names of 4 or 5 large cap pharmaceutical companies that are buyable now. Also I'm looking for 4 or 5 Biotech companies with one drug in the market making money and maybe something in the pipeline that looks like it has a good future? for example TGTX.

Upvote 5

Read Answer Asked by Mark on January 09, 2025

• Amgen Inc. (AMGN $294.62)
  • $294.62 P/E (TTM): 24.15X Cap: $158.61B
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• Regeneron Pharmaceuticals Inc. (REGN $563.86)
  • $563.86 P/E (TTM): 14.68X Cap: $59.76B
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• Vertex Pharmaceuticals Incorporated (VRTX $421.15)
  • $421.15 P/E (TTM): 29.08X Cap: $107.97B
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• Exact Sciences Corporation (EXAS $59.32)
  • $59.32 Cap: $10.93B
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• iShares Biotechnology ETF (IBB $151.99)
  • $151.99 P/E (TTM): 18.7X Cap: $6.18B
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• SPDR Biotech ETF (XBI $105.44)
  • $105.44 P/E (TTM): 15.46X Cap: $6.26B
  • View XBI Profile
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Q: Hello 5i,

Wondering if you have any recommendations in the Biometrics category, either ETF or stock? And any particular thoughts regarding current valuations and future prospects versus other opportunities?

Thanks for your feedback.

Ralph

Upvote 1

Read Answer Asked by ralph on September 09, 2024

• Duke Energy Corporation (Holding Company) (DUK $125.23)
  • $125.23 P/E (TTM): 20.42X Cap: $97.38B
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• NextEra Energy Inc. (NEE $84.04)
  • $84.04 P/E (TTM): 29.09X Cap: $173.06B
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• Xylem Inc. New (XYL $148.19)
  • $148.19 P/E (TTM): 38.58X Cap: $36.07B
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• Agnico Eagle Mines Limited (AEM $236.67)
  • $236.67 P/E (TTM): 34.45X Cap: $118.97B
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• American Water Works Company Inc. (AWK $141.03)
  • $141.03 P/E (TTM): 25.68X Cap: $27.51B
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• iShares Biotechnology ETF (IBB $151.99)
  • $151.99 P/E (TTM): 18.7X Cap: $6.18B
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• Invesco Water Resources ETF (PHO $73.60)
  • $73.60 P/E (TTM): 28.38X Cap: $2.27B
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• SPDR Biotech ETF (XBI $105.44)
  • $105.44 P/E (TTM): 15.46X Cap: $6.26B
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• Cameco Corporation (CCJ $86.21)
  • $86.21 P/E (TTM): 96.76X Cap: $37.53B
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• Invesco S&P Global Water Index ETF (CGW $64.01)
  • $64.01 P/E (TTM): 25.82X Cap: $1B
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• First Trust Water ETF (FIW $114.21)
  • $114.21 P/E (TTM): 26.33X Cap: $1.96B
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• Karora Resources Inc. (KRR $6.70)
  • $6.70 P/E (TTM): 85.51X Cap: $1.19B
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Q: Aside from AI what industries do you think will do well over the next year, both CDA and USA? Can you pls recommend specific stocks or ETFs in those industries?

Upvote 24

Read Answer Asked by Ron on May 23, 2024

• SPDR Biotech ETF (XBI $105.44)
  • $105.44 P/E (TTM): 15.46X Cap: $6.26B
  • View XBI Profile
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• argenx SE (ARGX $798.94)
  • $798.94 Cap: $48.72B
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Q: What are your thoughts on the portfolio diversification and growth potential of these securities? Thx!

Upvote 1

Read Answer Asked by David on March 06, 2024

• SPDR Biotech ETF (XBI $105.44)
  • $105.44 P/E (TTM): 15.46X Cap: $6.26B
  • View XBI Profile
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Q: Hi 5i, Is it a good time to invest in a biotech ETF such as XBI? 5 to 10 year hold. Would you wait for the markets to stabilize?

Thanks

Upvote 0

Read Answer Asked by Donald on June 06, 2022

• Stryker Corporation (SYK $375.29)
  • $375.29 P/E (TTM): 48.91X Cap: $143.47B
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• iShares Global Healthcare Index ETF (CAD-Hedged) (XHC $67.58)
  • $67.58 P/E (TTM): 25.66X Cap: $502M
  • View XHC Profile
  • View Questions on XHC
• SPDR Biotech ETF (XBI $105.44)
  • $105.44 P/E (TTM): 15.46X Cap: $6.26B
  • View XBI Profile
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• WELL Health Technologies Corp. (WELL $6.01)
  • $6.01 Cap: $1.52B
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• Andlauer Healthcare Group Inc. Subordinate Voting Shares (AND $51.96)
  • $51.96 P/E (TTM): 30.56X Cap: $2.03B
  • View AND Profile
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Q: Two part question, deduct as many points as you like.

I'm just wondering if anyone at 5I has glanced at the 195 page(!!) short report that Spruce Point put out last week on Stryker. Anything in particular to be concerned about? I own it in my RRSP, and have been slowly adding to my position. It is the only stock that I own in the health care sector.

Also, what would be your top pick, CA or US in this sector, if I wanted to diversify my portfolio?

Thank you for all that you do.

Upvote 0

Read Answer Asked by Ed on April 12, 2022

• SPDR Biotech ETF (XBI $105.44)
  • $105.44 P/E (TTM): 15.46X Cap: $6.26B
  • View XBI Profile
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Q: I think this bio tech etc has recently had a tough time. I know that you recommend it. But,I was wondering whether you think this might be it's time to recuperate it's losses? Do you have something that you like more than this. If so, why? As always thanks for the great service

Upvote 0

Read Answer Asked by joseph on February 04, 2022

• Intuitive Surgical Inc. (ISRG $448.09)
  • $448.09 P/E (TTM): 62.63X Cap: $160.62B
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• AbbVie Inc. (ABBV $231.24)
  • $231.24 P/E (TTM): 110.14X Cap: $408.49B
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• Cummins Inc. (CMI $436.35)
  • $436.35 P/E (TTM): 20.22X Cap: $60.12B
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• Lockheed Martin Corporation (LMT $514.02)
  • $514.02 P/E (TTM): 28.7X Cap: $120B
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• Stryker Corporation (SYK $375.29)
  • $375.29 P/E (TTM): 48.91X Cap: $143.47B
  • View SYK Profile
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• Health Care Select Sector SPDR (XLV $144.51)
  • $144.51 P/E (TTM): 23.15X Cap: $35.86B
  • View XLV Profile
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• iShares U.S. Medical Devices ETF (IHI $60.47)
  • $60.47 P/E (TTM): 28.17X Cap: $4.15B
  • View IHI Profile
  • View Questions on IHI
• SPDR Biotech ETF (XBI $105.44)
  • $105.44 P/E (TTM): 15.46X Cap: $6.26B
  • View XBI Profile
  • View Questions on XBI
• Vanguard Industrials ETF (VIS $300.22)
  • $300.22 P/E (TTM): 23.95X Cap: $5.83B
  • View VIS Profile
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• Industrial Select Sector SPDR (XLI $155.59)
  • $155.59 P/E (TTM): 25.91X Cap: $24.14B
  • View XLI Profile
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• Generac Holdlings Inc. (GNRC $171.33)
  • $171.33 P/E (TTM): 27.31X Cap: $9.72B
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• Guardant Health Inc. (GH $65.32)
  • $65.32 Cap: $8.14B
  • View GH Profile
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• Jacobs Solutions Inc. (J $157.36)
  • $157.36 P/E (TTM): 38.83X Cap: $18.80B
  • View J Profile
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Q: Hi group I am light on Health care + Manufacturing stocks what are your top 3 recommendations in both stocks / ETFs and why Thanks for your guidance

Upvote 0

Read Answer Asked by Terence on August 11, 2021

• Intuitive Surgical Inc. (ISRG $448.09)
  • $448.09 P/E (TTM): 62.63X Cap: $160.62B
  • View ISRG Profile
  • View Questions on ISRG
• AbbVie Inc. (ABBV $231.24)
  • $231.24 P/E (TTM): 110.14X Cap: $408.49B
  • View ABBV Profile
  • View Questions on ABBV
• iShares Biotechnology ETF (IBB $151.99)
  • $151.99 P/E (TTM): 18.7X Cap: $6.18B
  • View IBB Profile
  • View Questions on IBB
• SPDR Biotech ETF (XBI $105.44)
  • $105.44 P/E (TTM): 15.46X Cap: $6.26B
  • View XBI Profile
  • View Questions on XBI
• Guardant Health Inc. (GH $65.32)
  • $65.32 Cap: $8.14B
  • View GH Profile
  • View Questions on GH
• ARK Genomic Revolution ETF (ARKG $32.13)
  • $32.13 P/E (TTM): 22.05X Cap: $1.02B
  • View ARKG Profile
  • View Questions on ARKG

Q: Is this the season for owning Biotech stocks , if so, which ones do you favour ? ...
Am I just better off owning stocks, ETFs , or the spider .
I have never done well in that subsection, so I am hesitant .

Thank you

Upvote 0

Read Answer Asked by Thomas on July 21, 2021

• Intuitive Surgical Inc. (ISRG $448.09)
  • $448.09 P/E (TTM): 62.63X Cap: $160.62B
  • View ISRG Profile
  • View Questions on ISRG
• AbbVie Inc. (ABBV $231.24)
  • $231.24 P/E (TTM): 110.14X Cap: $408.49B
  • View ABBV Profile
  • View Questions on ABBV
• Gamehost Inc. (GH $11.65)
  • $11.65 P/E (TTM): 9.35X Cap: $240M
  • View GH Profile
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  • View Reports on GH
• iShares Biotechnology ETF (IBB $151.99)
  • $151.99 P/E (TTM): 18.7X Cap: $6.18B
  • View IBB Profile
  • View Questions on IBB
• SPDR Biotech ETF (XBI $105.44)
  • $105.44 P/E (TTM): 15.46X Cap: $6.26B
  • View XBI Profile
  • View Questions on XBI

Q: can you recommend a Canadian and Us biotech etf and stock?
thanks

Upvote 0

Read Answer Asked by Mary on June 10, 2021

• Intuitive Surgical Inc. (ISRG $448.09)
  • $448.09 P/E (TTM): 62.63X Cap: $160.62B
  • View ISRG Profile
  • View Questions on ISRG
• AbbVie Inc. (ABBV $231.24)
  • $231.24 P/E (TTM): 110.14X Cap: $408.49B
  • View ABBV Profile
  • View Questions on ABBV
• BMO Equal Weight REITs Index ETF (ZRE $22.25)
  • $22.25 P/E (TTM): 19.26X Cap: $591M
  • View ZRE Profile
  • View Questions on ZRE
• Vanguard Real Estate Index Fund ETF (VNQ $89.76)
  • $89.76 P/E (TTM): 33.61X Cap: $32.94B
  • View VNQ Profile
  • View Questions on VNQ
• Health Care Select Sector SPDR (XLV $144.51)
  • $144.51 P/E (TTM): 23.15X Cap: $35.86B
  • View XLV Profile
  • View Questions on XLV
• iShares U.S. Medical Devices ETF (IHI $60.47)
  • $60.47 P/E (TTM): 28.17X Cap: $4.15B
  • View IHI Profile
  • View Questions on IHI
• SPDR Biotech ETF (XBI $105.44)
  • $105.44 P/E (TTM): 15.46X Cap: $6.26B
  • View XBI Profile
  • View Questions on XBI
• Guardant Health Inc. (GH $65.32)
  • $65.32 Cap: $8.14B
  • View GH Profile
  • View Questions on GH
• iShares U.S. Real Estate ETF (IYR $95.31)
  • $95.31 P/E (TTM): 33.32X Cap: $3.63B
  • View IYR Profile
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Q: Hi group need more exposure to real estate and health care - could you recommend a few in each sector also a few ETF would be helpful. I have some ready cash to deploy but am a bit queasy about investing into todays market feels oversold? also India , South America are struggling with COVID what's you thoughts (leaning towards waiting until Virus is better controlled. Wait or jump in Appreciate your thoughts

Upvote 0

Read Answer Asked by Terence on April 28, 2021

• SPDR Biotech ETF (XBI $105.44)
  • $105.44 P/E (TTM): 15.46X Cap: $6.26B
  • View XBI Profile
  • View Questions on XBI

Q: I am interested in investing in some US ETFs. I would put these into an RRSP account. Would there be tax consequences re the CRA or IRS in doing so? I imagine that there would be tax complications if they were held in a margin account.

Upvote 0

Read Answer Asked by Catherine on April 23, 2021

• Amgen Inc. (AMGN $294.62)
  • $294.62 P/E (TTM): 24.15X Cap: $158.61B
  • View AMGN Profile
  • View Questions on AMGN
• Biogen Inc. (BIIB $150.97)
  • $150.97 P/E (TTM): 14.57X Cap: $22.13B
  • View BIIB Profile
  • View Questions on BIIB
• Regeneron Pharmaceuticals Inc. (REGN $563.86)
  • $563.86 P/E (TTM): 14.68X Cap: $59.76B
  • View REGN Profile
  • View Questions on REGN
• Merck & Company Inc. (MRK $86.40)
  • $86.40 P/E (TTM): 13.51X Cap: $215.80B
  • View MRK Profile
  • View Questions on MRK
• iShares Biotechnology ETF (IBB $151.99)
  • $151.99 P/E (TTM): 18.7X Cap: $6.18B
  • View IBB Profile
  • View Questions on IBB
• SPDR Biotech ETF (XBI $105.44)
  • $105.44 P/E (TTM): 15.46X Cap: $6.26B
  • View XBI Profile
  • View Questions on XBI
• Guardant Health Inc. (GH $65.32)
  • $65.32 Cap: $8.14B
  • View GH Profile
  • View Questions on GH
• ARK Genomic Revolution ETF (ARKG $32.13)
  • $32.13 P/E (TTM): 22.05X Cap: $1.02B
  • View ARKG Profile
  • View Questions on ARKG

Q: hi group I asked a question on bio tech last Wed - no response as of yet ? - please follow up. The question was do you like the sector/ and what ETFs /top 3 individual stocks do you recommend thanks

Upvote 0

Read Answer Asked by Terence on October 19, 2020

• SPDR Biotech ETF (XBI $105.44)
  • $105.44 P/E (TTM): 15.46X Cap: $6.26B
  • View XBI Profile
  • View Questions on XBI
• ARK Genomic Revolution ETF (ARKG $32.13)
  • $32.13 P/E (TTM): 22.05X Cap: $1.02B
  • View ARKG Profile
  • View Questions on ARKG

Q: HI 5I gang

Our question is about biotech etf"s Looking for an etf that will cover covid vacine and treatments. A couple of ideas please.
thanks as always

Ken & Cindy

Upvote 0

Read Answer Asked by cindy on August 19, 2020

• Johnson & Johnson (JNJ $189.69)
  • $189.69 P/E (TTM): 20.2X Cap: $456.83B
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• Pfizer Inc. (PFE $25.68)
  • $25.68 P/E (TTM): 14.06X Cap: $146B
  • View PFE Profile
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• iShares Biotechnology ETF (IBB $151.99)
  • $151.99 P/E (TTM): 18.7X Cap: $6.18B
  • View IBB Profile
  • View Questions on IBB
• SPDR Biotech ETF (XBI $105.44)
  • $105.44 P/E (TTM): 15.46X Cap: $6.26B
  • View XBI Profile
  • View Questions on XBI
• Vanguard Health Care ETF (VHT $269.31)
  • $269.31 P/E (TTM): 23.36X Cap: $15.33B
  • View VHT Profile
  • View Questions on VHT
• Moderna Inc. (MRNA $27.92)
  • $27.92 Cap: $10.86B
  • View MRNA Profile
  • View Questions on MRNA

Q: Can you recommend a good ETF probably US based, which has companies in the forefront of corona vaccine development/demonstration, as well as corona related testing and diagnosis.

Upvote 0

Read Answer Asked by Vinod on April 06, 2020

• iShares Biotechnology ETF (IBB $151.99)
  • $151.99 P/E (TTM): 18.7X Cap: $6.18B
  • View IBB Profile
  • View Questions on IBB
• SPDR Biotech ETF (XBI $105.44)
  • $105.44 P/E (TTM): 15.46X Cap: $6.26B
  • View XBI Profile
  • View Questions on XBI
• ARK Genomic Revolution ETF (ARKG $32.13)
  • $32.13 P/E (TTM): 22.05X Cap: $1.02B
  • View ARKG Profile
  • View Questions on ARKG

Q: Is there a good small cap biotech ETF you would recommend ?

Upvote 0

Read Answer Asked by david on May 21, 2019

• iShares Biotechnology ETF (IBB $151.99)
  • $151.99 P/E (TTM): 18.7X Cap: $6.18B
  • View IBB Profile
  • View Questions on IBB
• SPDR Biotech ETF (XBI $105.44)
  • $105.44 P/E (TTM): 15.46X Cap: $6.26B
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• Vanguard Health Care ETF (VHT $269.31)
  • $269.31 P/E (TTM): 23.36X Cap: $15.33B
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Q: Could you please recommend an ETF relating to the healthcare sector please (possibly 3)? Should it be North American focused or more Global?
Thanks!

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Read Answer Asked by Brian on January 22, 2018