Q: I've been watching REGN slide from US$650 to under US$500 over the last few months. Is it just out of favour? The metrics seem ok (for a biotech) and analysts still seem to like it. What's your opinion on opening a position under $500? Thanks.
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Investment Q&A
Not investment advice or solicitation to buy/sell securities. Do your own due diligence and/or consult an advisor.
Q: Hi there,
DMTK I came across DermTech listening to a MF US stock advisor live session on 10X opportunities. I spent some time reviewing their most recent earnings transcript and other research and the technology for non invasive detection of skin cancer seems powerful but super early in terms of adoption (a brief excerpt is below). I am considering buying for TFSA and have the following questions:
1. What is your general opinion?
2. Do you have any information on how a dermatologist would be paid for using this test vs surgery? My fear would be that the tech is amazing but dermatologists may not use it if it would reduce their revenue
"Currently, approximately 25 surgical biopsies are performed to find one melanoma. And despite all this cutting, the negative predictive value of this pathway is only about 83%, which means the probability of missing melanoma is approximately 17%. The PLA reduces the number of surgical biopsies needed to identify melanomas by approximately 10-fold and increases the negative predictive value so 99%, meaning the PLA has less than 1% probability of missing the disease. DermTech is effectively bringing melanoma diagnosis into the 21st century by transforming it from a pathway to subjective, invasive, inaccurate and costly to one that is objective, non-invasive, highly accurate, and less costly."
DMTK I came across DermTech listening to a MF US stock advisor live session on 10X opportunities. I spent some time reviewing their most recent earnings transcript and other research and the technology for non invasive detection of skin cancer seems powerful but super early in terms of adoption (a brief excerpt is below). I am considering buying for TFSA and have the following questions:
1. What is your general opinion?
2. Do you have any information on how a dermatologist would be paid for using this test vs surgery? My fear would be that the tech is amazing but dermatologists may not use it if it would reduce their revenue
"Currently, approximately 25 surgical biopsies are performed to find one melanoma. And despite all this cutting, the negative predictive value of this pathway is only about 83%, which means the probability of missing melanoma is approximately 17%. The PLA reduces the number of surgical biopsies needed to identify melanomas by approximately 10-fold and increases the negative predictive value so 99%, meaning the PLA has less than 1% probability of missing the disease. DermTech is effectively bringing melanoma diagnosis into the 21st century by transforming it from a pathway to subjective, invasive, inaccurate and costly to one that is objective, non-invasive, highly accurate, and less costly."
Q: Hi Peter and team,
I am a new member and have been enjoying the question and answer section.
I would like you take on these two stocks and wether you prefer one to the other.
Thanks
Javad
I am a new member and have been enjoying the question and answer section.
I would like you take on these two stocks and wether you prefer one to the other.
Thanks
Javad
Q: Could I please have your view on ET. (US) Is this good for a long term hold? Will it ever get back in favor? Is there better places to be? Thanks in advance. Appreciate your inpu.t.
Q: Hi, any news causing the drop of MGNI today? Are there any reasons for long term concerns?
Thank-you.
Thank-you.
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Ichor Holdings (ICHR $18.29)
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Invitae Corporation (NVTA)
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Tronox Holdings plc (UK) (TROX $3.31)
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Celsius Holdings Inc. (CELH $60.70)
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Magnite Inc. (MGNI $17.50)
Q: What are your top five Canadian and top five US small cap growth companies in terms of reward to risk, for a 5 year timeframe?
Q: As always, thank you for your great service. Would you be a buyer at these levels or would you wait for a pullback. Looking at 5 year hold on this company.
Thanks
Thanks
Q: Hi,
Of these relatively new biotech companies that have or will soon be IPO'ing, Repare Therapeutics (June IPO) and Abcellera Biotech (upcoming IPO), where would you put some play money? A bit of both? Or another recent IPO/choice altogether?
It seems that Abcellera might be a little ahead of the game wrt being profitable already. And I'm pretty sure given the expected interest, I may have to get this initially on the open market.
Are there any things from a finance view we should be aware of with these IPO's other than biotechs can be more risky dependent on clinical trial results, etc..
Repare has done well since its IPO in June.
Can you pls also add Repare to your db? It did not come up in a text or stock symbol search.
Cheers,
SteveMc
Of these relatively new biotech companies that have or will soon be IPO'ing, Repare Therapeutics (June IPO) and Abcellera Biotech (upcoming IPO), where would you put some play money? A bit of both? Or another recent IPO/choice altogether?
It seems that Abcellera might be a little ahead of the game wrt being profitable already. And I'm pretty sure given the expected interest, I may have to get this initially on the open market.
Are there any things from a finance view we should be aware of with these IPO's other than biotechs can be more risky dependent on clinical trial results, etc..
Repare has done well since its IPO in June.
Can you pls also add Repare to your db? It did not come up in a text or stock symbol search.
Cheers,
SteveMc
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Costco Wholesale Corporation (COST $930.01)
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Gilead Sciences Inc. (GILD $117.18)
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Alphabet Inc. (GOOG $237.49)
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Microsoft Corporation (MSFT $510.96)
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QUALCOMM Incorporated (QCOM $153.59)
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Starbucks Corporation (SBUX $78.46)
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AbbVie Inc. (ABBV $230.50)
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Duke Energy Corporation (Holding Company) (DUK $127.02)
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JPMorgan Chase & Co. (JPM $300.89)
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Verizon Communications Inc. (VZ $39.85)
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DocuSign Inc. (DOCU $68.40)
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Berkshire Hathaway Inc. (BRK.B $489.13)
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Trane Technologies plc (TT $414.14)
Q: good afternoon 5i,
On December 3 you responded to a question by Curtis by saying, "We also think a low cost index product for the majority of a portfolio overlain with a basket of individual stocks to generate alpha is also a pretty good strategy, for those inclined to hold 6 or 7 individual stocks. "
This is a strategy that I more or less use, at least for my US and International holdings. I haven't done this with my Canadian holdings because of capital gains, which would imply tax, and also because it seems to me that the Canadian etf's are heavily weighted towards the few sectors we have in Canada. Therefore, I think I would be better in individual stocks rather than an etf. I would appreciate your take on that perspective.
Also, I am wondering which four or five stocks you would look at in the US for such a strategy for a retired person. And how would you weight them given that an etf strategy was used. The stocks I have listed are the ones I own. How would they fit in such a portfolio? The only one I might kick out for someone my age is Docusign. Any others that could be suggested?
Thanks for the great service
On December 3 you responded to a question by Curtis by saying, "We also think a low cost index product for the majority of a portfolio overlain with a basket of individual stocks to generate alpha is also a pretty good strategy, for those inclined to hold 6 or 7 individual stocks. "
This is a strategy that I more or less use, at least for my US and International holdings. I haven't done this with my Canadian holdings because of capital gains, which would imply tax, and also because it seems to me that the Canadian etf's are heavily weighted towards the few sectors we have in Canada. Therefore, I think I would be better in individual stocks rather than an etf. I would appreciate your take on that perspective.
Also, I am wondering which four or five stocks you would look at in the US for such a strategy for a retired person. And how would you weight them given that an etf strategy was used. The stocks I have listed are the ones I own. How would they fit in such a portfolio? The only one I might kick out for someone my age is Docusign. Any others that could be suggested?
Thanks for the great service
Q: Hi there,
What are your thoughts about taking a position in DKNG long term? What do you value the stock in USD?
What are your thoughts about taking a position in DKNG long term? What do you value the stock in USD?
Q: Hertz HTZGQ Any comments on this stock. cheers
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Gilead Sciences Inc. (GILD $117.18)
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ONEOK Inc. (OKE $69.09)
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Keyera Corp. (KEY $43.87)
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WELL Health Technologies Corp. (WELL $5.19)
Q: Good Morning, I purchased 2 stocks for their dividend income, and to hold for at least 5-10 years. OKE is about 3.7% of my US portfolio and KEY at 2.9% of my Canadian portfolio. Am thinking of selling and taking advantage of the tax loss since they are underperforming. Would this be a wise move or should I stay the course and keep them. If I do sell I was thinking of adding X and Well along with DUK and GILD...thoughts or suggestions?
Q: Hi,
Will you recommend this company?
Thanks,
Morris
Will you recommend this company?
Thanks,
Morris
Q: Could you please comment on their results?
Thanks,
Milan
Thanks,
Milan
Q: Hello team,
As you know, AMD is acquiring Xilinx whereby XLNX shareholders Will receive 1.7234 share of AMD for each share owned, equal to $143 in cash.
I have 100 shares of XLNX and have three questions for you.
1- Are these numbers fixed or would change based on the market at the time of closing of the deal?
2- Would you sell your XLNX shares or would you think they would be much worth more following the merger?
3- Would you add more now and if yes how would you avoid partial shares/odd lots following the merger.
I always wonder what I do without 5i knowledge and honesty....Thank you for your everyday work, everyone at 5i.
As you know, AMD is acquiring Xilinx whereby XLNX shareholders Will receive 1.7234 share of AMD for each share owned, equal to $143 in cash.
I have 100 shares of XLNX and have three questions for you.
1- Are these numbers fixed or would change based on the market at the time of closing of the deal?
2- Would you sell your XLNX shares or would you think they would be much worth more following the merger?
3- Would you add more now and if yes how would you avoid partial shares/odd lots following the merger.
I always wonder what I do without 5i knowledge and honesty....Thank you for your everyday work, everyone at 5i.
Q: Hi group i am still holding W - down 10% - finding it hard to justify keeping the stock . I expected the last quarterly results to drive up the price its now well of its high ( down approx. $100 US). It is still a hold or should I sell. (I own 70 shares Thanks for your thought's on this .
Q: Your thoughts on this company please and thanks , Bill
Q: If you could only buy 1 position, would it be TTD or U?
Alternatively, would your preference be to exit a position in Facebook and buy both of these as TTD and Facebook are both driven by online advertising?
Alternatively, would your preference be to exit a position in Facebook and buy both of these as TTD and Facebook are both driven by online advertising?
Q: What do you think of 3M with regards to share appreciation long term? Thanks for your great service as always.
Q: A lot of commentators are saying sectors other than technology should do well in what is seen as a bull market. Do you believe buying an industrial etf is a reasonable investment? I am underweight industrials. Thanks, Bill